Nanofabulous Seminar: Toward Autonomous Science: Nanotechnology and the Rise of Self-Learning Machines
This lecture explores the dynamic interplay between artificial intelligence (AI) and nanotechnology, highlighting how each drives the other forward. While AI accelerates material discovery, sensing, and diagnostics, nanotechnology enables the development of advanced hardware such as neuromorphic and quantum systems. Together, they are paving the way for the 5th paradigm of science, where machines autonomously generate knowledge, design experiments, and interpret data with minimal human input. Case studies in biosensing and image analysis illustrate these trends. The lecture will also address the societal implications of this shift toward machine-led scientific discovery.
Prof Osvaldo N. Oliveira Jr.
Director, the São Carlos Institute of Physics
The University of São Paulo, Brazil
10:00am, 31/07/2025
Melbourne Centre for Nanofabrication
151 Wellington Road, Clayton, 3168
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Meeting ID: 874 0886 6047 and passcode:971252
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Nanofabulous Seminar: Development of Smart Micro-/Nano-formulations for Tumor-targeted Delivery
Treatment of tumors has been less desired due to the presence of tumor microenvironment (TME) comprising unique characteristics such as pH reduction, redox imbalance, dynamic hypoxia, complex vasculature, multidrug resistance, and so on, which barricaded the delivery of medicines to tumor lesions. My research aims to establish smart micro-/nano-technological systems that could either (1) ensure a safe delivery passage for medicinal formulations to penetrate the TME to reach tumor sites, (2) overcoming drug efflux-based multidrug resistance, (3) remodulate TME to enhance the imaging and therapeutic efficacies of tumors, or (4) encapsulate and promote sustained drug release. Overall, my research could contribute to the oncology field by providing innovative approaches that improve the combating of tumors.
Dr. Liang Ee Low
Lecturer in Monash University Malaysia
3:00pm, 15/07/2025
Melbourne Centre for Nanofabrication
151 Wellington Road, Clayton, 3168
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Meeting ID: 837 2690 9791 passcode: 554406
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Nanofabulous Seminar: Unveiling the Impact of Nanoscale Membrane Deformation in Cells
Cell membranes serve as a central platform to host a variety of proteins essential for cellular activities such as cell signaling, morphogenesis, and membrane trafficking. At the same time, the membranes also undergo drastic morphological changes in a number of essential processes, such as endocytosis, intracellular trafficking, and cytokinesis, etc.
An intriguing yet challenging question to answer is whether and how the shapes of the membrane impact the dynamics of membrane proteins or the periphery proteins interacting with the membrane.
However, membrane shape changes often happen at sub-micro to the nanoscale, which is approaching the limit of conventional microscopy imaging resolution and difficult to examine quantitatively. In this talk, I will introduce our efforts in employing vertically aligned nanostructures to generate defined membrane topography in live cells and in vitro. We will discuss our findings on the membrane curvature-guided accumulation of membrane proteins, including oncogenic Ras proteins and viral proteins. In addition to plasma membrane, we also explore the nanoscale topography guidance on nuclear membrane and its implication in differentiating malignant cancer cells. We envision more new insights would be revealed by bridging advanced nanotechnology to nanoscale dynamics at cell membrane.
Dr. Wenting Zhao
School of Chemistry, Chemical Engineering and Biotechnology
Nanyang Technological University, Singapore.
11:00am, 14/07/2025
Melbourne Centre for Nanofabrication
151 Wellington Road, Clayton, 3168
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Meeting ID: 836 5781 3944 passcode: 303563
